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Human Chorionic Gonadotropin (HCG) is an injectable hormone that mimics the effects of Luteinizing Hormone (LH), a crucial reproductive hormone. The 10,000 IU dosage is a high-strength amount, typically provided as a powder that must be mixed with a liquid (diluent) before injection.

• In Women (Fertility): It is mainly used as a single, critical "trigger shot" to force the final release of mature eggs (ovulation) during a monitored fertility cycle (like IVF or IUI).
• In Men (Hormone Therapy): It is mixed into a multi-dose solution and used for smaller, frequent injections (e.g., 500 IU two to three times per week) to stimulate the testicles to produce testosterone and maintain sperm count.

The HCG 10,000 IU vial requires two main steps: Reconstitution (Mixing) and Injection. Always follow your doctor's specific instructions, as protocols vary widely.

1. Gather Supplies: Get the HCG powder vial, the diluent vial (sterile or bacteriostatic water), a mixing syringe, and a mixing needle.
2. Mix: Wipe the tops of both vials with alcohol. Draw the exact amount of diluent prescribed by your doctor (e.g., 1 mL, 2 mL, or 10 mL) into the mixing syringe and inject it into the HCG powder vial.
3. Dissolve: Do NOT shake. Gently roll the vial between your palms until the powder is completely dissolved and the liquid is clear.
4. Store: Store the mixed vial immediately in the refrigerator (36∘F to 46∘F).

1. Injection Route: The injection is given either Subcutaneously (SC) (into the fat layer, typically the abdomen or thigh) or Intramuscularly (IM) (into the muscle, typically the upper outer buttock or thigh), as prescribed.
2. Dosing (Women's Trigger): You will usually inject the entire reconstituted vial as a single injection at the precise time dictated by your physician.
3. Dosing (Men's Weekly Dose): Use an insulin syringe to draw the small prescribed volume (e.g., 0.25 mL) for your dose. This is usually given SC two or three times per week.
4. Technique: Clean the injection site with an alcohol swab and let it air-dry. Pinch the skin for SC injection. Insert the needle completely, push the plunger slowly to inject the medication, wait a few seconds, and then withdraw the needle.

1. How long does the mixed vial last?Once mixed and refrigerated, the solution typically remains stable for 30 to 60 days. Any unused portion must be discarded after this period, even if there is medication left.

2. Will this dose make me test positive for pregnancy? Yes. In women, the HCG trigger shot will cause a temporary false positive on home or blood pregnancy tests for up to two weeks. This is because HCG is the hormone detected by the test. You must wait for the hormone to clear your system before taking a reliable test, as advised by your doctor.

3. What is the most significant risk for women taking this dose?The most significant risk is Ovarian Hyperstimulation Syndrome (OHSS), which causes severe swelling, pain, and fluid retention in the abdomen. If you experience severe abdominal pain or sudden, rapid weight gain, contact your doctor immediately.

4. Can I use this HCG dosage for weight loss? No. HCG is not approved by the U.S. FDA for weight loss. Any weight reduction observed on an "HCG diet" is attributed to the extreme calorie restriction involved, not the hormone itself.

5. Why is a 10,000 IU vial used for a man who only needs 500 IU doses?The 10,000 IU is simply the packaging size for the multi-dose vial. The hormone is mixed to a lower concentration (e.g., 1,000 IU/mL) so that a small volume (like 0.5 mL) can be measured and injected a few times per week, making the entire vial last for several weeks.